Wanna know what happens every time you add or subtract a zero to the scale of stuff? Well, then, check out this interactive Flash animation that shows the scale of the universe, from the shortest measurable length to the largest observable structures in the universe.
As nifty as that is, I still think the classic, Powers of Ten, holds up very well even after 35 years.
Both are awesome, but I have to give the Flash based one an extra point for including a Minecraft world size :)